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Search Results for " transforming growth factor β-2 "

Targets

5

Compounds

314

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8330 BIO-013077-01 TGF-beta/Smad
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
T1726 SB-431542 SB 431542 ALK , TGF-beta/Smad
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiatio...
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T16464 Pelubiprofen COX
Pelubiprofen, an orally active non-steroidal anti-inflammatory drug (NSAID) belonging to the 2-arylpropionic acid family, selectively inhibits COX-2 activity alongside COX activity and the transforming growth factor-β ac...
T35438 (5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxoz...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human Human Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-00413 TGF beta 2 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-05157 TGFBR2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-01009 TGFBI Protein, Human, Recombinant (His) Human HEK293
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-00231 TGF beta 2 Protein, Canine, Recombinant (His) Canine HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His) Rhesus HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00260 Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00259 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00238 Lefty-A Protein, Human, Recombinant (His) Human Human Cells
Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma...
TMPY-05810 TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-05508 TGFBR2 Protein, Human, Recombinant (hFc) Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D) Human E. coli
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPK-00329 TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated Human HEK293
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign...
TMPK-00328 TGFBR2 Protein, Human, Recombinant (mFc & Avi) Human HEK293
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign...
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-00431 BMP-4 Protein, Mouse, Recombinant (rFc) Mouse HEK293
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-03998 ANGPTL2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293) Human HEK293
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149) Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli.
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-02011 CD96 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00871 LAYN Protein, Human, Recombinant (hFc) Human HEK293
Layilin recently characterized as a 55 kDa transmembrane protein with homology to C-type lectins, is present in numerous cell lines and tissue extracts. As one of the adaptor proteins, talin mediates the interactions bet...
TMPY-00849 ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00850 ST2/IL-1 RL1 Protein, Human, Recombinant Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00748 Nectin-2 Protein, Human, Recombinant Human HEK293
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein a...
TMPY-00005 FGF-8a Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-02358 CD98 Protein, Mouse, Recombinant (His) Mouse HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Mouse Human Cells
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-04356 GSK3B Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc) Human HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a) Human E. coli
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPY-01199 CD74 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05427 CD19 Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His) Human HEK293
BTN3A1 has the structure of a type I receptor of the Ig superfamily and is part of a family of seven BTN receptors encoded by genes in the MHC. BTN molecules are composed of two Ig domains (IgV, IgC2), a single transmemb...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 cells.
TMPY-04829 G-CSF Protein, Human, Recombinant Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-01935 C-Kit Protein, Human, Recombinant (His) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
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TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: Human Cells
TGF beta 2 Protein, Mouse, Recombinant (His)
TMPY-00413
Species: Mouse
Expression System: HEK293
TGF beta 2 Protein, Mouse/Rat, Recombinant
TMPJ-00261
Species: Mouse,Rat
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
Species: Human
Expression System: Baculovirus-Insect Cells
TGFBI Protein, Human, Recombinant (His)
TMPY-01009
Species: Human
Expression System: HEK293
TGFBR2 Protein, Mouse, Recombinant (His)
TMPJ-00335
Species: Mouse
Expression System: Human Cells
TGF beta 2 Protein, Canine, Recombinant (His)
TMPY-00231
Species: Canine
Expression System: HEK293
TGF beta 2 Protein, Rhesus, Recombinant (His)
TMPY-04577
Species: Rhesus
Expression System: HEK293
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00260
Species: Human
Expression System: Human Cells
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00259
Species: Human
Expression System: Human Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05314
Species: Mouse
Expression System: HEK293
Lefty-A Protein, Human, Recombinant (His)
TMPJ-00238
Species: Human
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05810
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (hFc)
TMPY-05508
Species: Human
Expression System: HEK293
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TMPJ-00334
Species: Mouse
Expression System: Human Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TMPJ-00333
Species: Mouse
Expression System: Human Cells
BMP-4 Protein, Human, Recombinant (E399D)
TMPY-06842
Species: Human
Expression System: E. coli
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00329
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TMPK-00328
Species: Human
Expression System: HEK293
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00622
Species: Cynomolgus
Expression System: Human Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPJ-00772
Species: Mouse
Expression System: Human Cells
BMP-4 Protein, Mouse, Recombinant (rFc)
TMPY-00431
Species: Mouse
Expression System: HEK293
ANGPTL2 Protein, Mouse, Recombinant (hFc)
TMPY-03998
Species: Mouse
Expression System: HEK293
GDNF Protein, Human, Recombinant (HEK293)
TMPY-02792
Species: Human
Expression System: HEK293
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
TMPY-05288
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
TMPY-04116
Species: Human
Expression System: E. coli
CD96 Protein, Human, Recombinant (His)
TMPY-02011
Species: Human
Expression System: HEK293
LAYN Protein, Human, Recombinant (hFc)
TMPY-00871
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
TMPY-00849
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant
TMPY-00850
Species: Human
Expression System: HEK293
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
TMPY-00891
Species: Human
Expression System: HEK293
Nectin-2 Protein, Human, Recombinant
TMPY-00748
Species: Human
Expression System: HEK293
FGF-8a Protein, Human, Recombinant
TMPY-00005
Species: Human
Expression System: E. coli
CD98 Protein, Mouse, Recombinant (His)
TMPY-02358
Species: Mouse
Expression System: HEK293
Clusterin Protein, Human, Recombinant (CLU34, His)
TMPY-01691
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
TMPY-00341
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
TMPJ-00850
Species: Mouse
Expression System: Human Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
TMPY-04396
Species: Human
Expression System: Baculovirus-Insect Cells
GSK3B Protein, Human, Recombinant (His)
TMPY-04356
Species: Human
Expression System: Baculovirus-Insect Cells
CLEC10A Protein, Human, Recombinant (hFc)
TMPY-02971
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (isoform a)
TMPY-02820
Species: Human
Expression System: E. coli
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05586
Species: Human
Expression System: HEK293
CD74 Protein, Human, Recombinant (His)
TMPY-01199
Species: Human
Expression System: HEK293
CD19 Protein, Human, Recombinant (hFc)
TMPY-05427
Species: Human
Expression System: HEK293
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
TMPY-04113
Species: Human
Expression System: E. coli
BTN3A1 Protein, Human, Recombinant (His)
TMPY-04844
Species: Human
Expression System: HEK293
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-01985
Species: Human
Expression System: HEK293
G-CSF Protein, Human, Recombinant
TMPY-04829
Species: Human
Expression System: HEK293
c-Kit Protein, Human, Recombinant (His)
TMPY-01935
Species: Human
Expression System: HEK293
TargetMol